Sisyphus, MD
The case for testing treatments against several diseases of aging.
Writing and resources
We build and share practical resources to accelerate longevity research.
Longevity Industrialized
Norn’s blog on longevity science and the work needed to advance it.
Ask not what AI can do for longevity. Ask what the longevity field can do for AI
The experiments and datasets longevity needs to make better use of AI.
Advancing Longevity Trials: Lessons from mTOR-Targeting Interventions
Lessons from human mTOR studies for the next generation of longevity trials.
Resources
Get started in longevity
Analyses
- Data gaps that bottleneck aging biomarker discoveryWhich human datasets are missing, and what would make aging biomarkers useful?
- Advancing longevity trials: lessons from mTOR-targeting interventionsWhat human mTOR studies can teach us about endpoints, safety and trial design.
- Gene therapy for common diseasesThe costs, delivery challenges and clinical opportunities beyond rare genetic diseases.
- How to design a clinical trial for agingCompare trial endpoints and strategies for testing treatments that affect multiple diseases.
Research proposals
Research planning tools
